Buy Oxazepam: Here you can buy the benzodiazepine oxazepam without a prescription. The drug most in demand in Europe that contains this active ingredient is Adumbran. Oxazepam is a substance of the benzodiazepine family, marketed as a medical drug. Like all benzodiazepine compounds, it has anxiolytic, hypnotic and sedative, anticonvulsant and muscle relaxant properties, but is mainly used as an anxiolytic to limit the distressing effects of anxiety, and sometimes as a hypnotic in the short-term treatment of insomnia when other treatments have failed.
Buy Oxazepam: Basic Facts
When you buy oxazepam, you have chosen a quality product. Oxazemap is an active metabolite of a wide range of other benzodiazepines, such as diazepam, ketazolam, temazepam, chlordiazepoxide, demoxazepam, halazepam, medazepam, prazepam, pinazepam and chlorazepate.
Being itself a product of the metabolism of other compounds including diazepam and temazepam, it was one of the first to be manufactured when this class of drugs was in full development. Compared to other substances introduced later, such as alprazolam, it is of moderate potency. Roche and Wyeth worked on the “3-hydroxy-benzodiazepine” derivatives. Wyeth first discovered and patented the structure and biological activity of oxazepam, which was first marketed in the USA in 1965.
The molecule has a benzene ring or A-ring (benzo) and two nitrogen atoms (diaza) as part of the 7-atom nitrogen heterocycle (azepine) or B-ring. Another phenyl ring is located at position 5 of the nitrogen ring. The halogen in position 7 of ring A promotes anxiolytic activity. Deletion of the double bond of the nitrogen in position 4 of ring B decreases the activity. The OH group in position 3 of ring B increases the polarity of the molecule, promotes glucuronoconjugation and faster elimination. The rigid structure at its centre can have hydrophobic groups on its surface in all 3 spatial dimensions. This architecture prevents hydrophobic collapse, allows 3D recognition with the protein and increases the chances of bioavailability.
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